Study: Brain-to-Fat Communication Pathway Critical to Longevity

UConn School of Medicine Researchers Discover Treatment That Can Extend Lifespan by 60-70 Days in Mice

Highlights:

• A new study identifies a critical communication pathway connecting the brain and the body's fat.
• Activation of this pathway in mice led to a significant increase in lifespan of 60-70 days.
• Mice that received the neuron activation treatment lived significantly longer than control mice.
• The research, published in the August 6 issue of Cell Metabolism, has implications for understanding and potentially treating age-related diseases.

A recent study conducted by researchers at the UConn School of Medicine has identified a critical communication pathway connecting the brain and the body's fat.

By activating this pathway in mice, the researchers were able to extend the lifespan of the animals by 60-70 days. These findings could have implications for understanding and treating age-related diseases.

The study, published in the August 6 issue of Cell Metabolism, was led by gerontologist Ming Xu.